Three straight days of closing ahead has the AEterna Zentaris chart on watch for continued upward pressure. Shares rose 8.5 percent on Tuesday to close near the high of the day on increased volume, which is a bullish sign as the stock nears resistance. Shares traded as low as $1.75 last week, but have recovered to close on Tuesday at $2.16 on Read More

The path to bring a new cancer drug to market can certainly be a long and bumpy road full of twists and turns.  It was about one month ago that the news hit of Aeterna Zentaris (TSX: AEZ)(NASDAQ: AEZS) and Keryx Biopharmaceuticals (NASDAQ: KERX) terminating their license agreement with respect to perifosine, an Akt inhibiting oral anticancer compound; giving back full North American rights to Aeterna. Read More

Keryx Biopharmaceuticals, Inc. (NASDAQ:KERX) reported recently that a manuscript entitled “Randomized Placebo-Controlled Phase II Trial of Perifosine Plus Capecitabine as Second- or Third-Line Therapy in Patients with Metastatic Colorectal Cancer” reporting Phase 2 activity of KRX-0401 (perifosine) in the treatment of patients with refractory, advanced colorectal cancer (mCRC), was selected for publication in the October 3, 2011 online edition of the Journal of Clinical Oncology.  Efficacy data from this study was presented in June 2010 at the 46th Annual Meeting of the American Society of Clinical Oncology.

According to the press release on Keryx’s website,

“Based on the data, in which the combination of P-CAP demonstrated statistical significance with respect to median overall survival and median time to tumor progression, the investigators concluded that the P-CAP combination showed promising clinical activity compared to single-agent capecitabine, and that the difference in clinical outcome seen with the addition of perifosine was impressive.”

KRX-0401 (perifosine) is in-licensed by Keryx from Aeterna Zentaris Inc. (NASDAQ:AEZS) in the United States, Canada and Mexico.

Keryx Biopharmaceuticals (KERX) Stock Quote and News:

Disclaimer: Neither http://www.otcshowcase.com nor its officers, directors, partners, employees or anyone involved in the publication of the website or newsletters (“us” or “we”) is a registered investment adviser or licensed broker-dealer in any jurisdiction whatsoever. Further, we are not qualified to provide any investment advice and we make no recommendation to purchase or sell any securities. The prior article is published as information only for our readers. otcshowcase.com is a third party publisher of news and research. Our site does not make recommendations, but offers information portals to research news, articles, stock lists and recent research. Nothing on our site should be construed as an offer or solicitation to buy or sell products or securities. This site is sometimes compensated by featured companies, news submissions and online advertising. Viper Enterprises, LLC (parent company of OTC Showcase) has received no compensation for this article from and owns no shares of the aforementioned company(ies). Please read and fully understand our entire disclaimer at http://www.otcshowcase.com/?page_id=190.

Zacks.com, a leader in investment research, has aptly noted the recent uptrend in the share price of Keryx Biopharmaceuticals over the last several weeks.  Zack’s “SmarTrend” analyzes over 5,000 securities simultaneously throughout the trading day and provides its subscribers with trend change alerts in real time.

According to Zack’s commentary on April 5, 2011,

“In the past 52 weeks, shares of Keryx Biopharmaceuticals have traded between a low of $3.03 and a high of $6.67 and are now at $5.05, which is 67% above that low price.

Keryx Biopharmaceuticals is currently above its 50-day moving average of $4.19 and above its 200-day moving average of $4.38. Look for these moving averages to climb to confirm the company’s upward momentum.

In the last five trading sessions, the 50-day MA has climbed 1.72% while the 200-day MA has risen 0.28%.”

Keryx Biopharmaceuticals is focused on the acquisition, development and commercialization of medically important pharmaceutical products for the treatment of cancer and renal disease. Keryx is developing KRX-0401 (perifosine), a novel, potentially first-in-class, oral anti-cancer agent that inhibits Akt activation in the phosphoinositide 3-kinase (PI3K) pathway, and also affects a number of other key signal transduction pathways, including the JNK pathway, all of which are pathways associated with programmed cell death, cell growth, cell differentiation and cell survival. KRX-0401 has demonstrated both safety and clinical efficacy in several tumor types, both as a single agent and in combination with novel therapies. KRX-0401 is currently in Phase 3 clinical development for both refractory advanced colorectal cancer and multiple myeloma, and in Phase 1 and 2 clinical development for several other tumor types. Each of the KRX-0401 Phase 3 studies is being conducted under a Special Protocol Assessment (SPA) agreement with the FDA. Keryx is also developing Zerenex (ferric citrate), an oral, ferric iron-based compound that has the capacity to bind to phosphate and form non-absorbable complexes. The Phase 3 clinical program of Zerenex in the treatment for hyperphosphatemia (elevated phosphate levels) in patients with end-stage renal disease is being conducted pursuant to an SPA agreement with the FDA. Keryx is headquartered in New York City.

Keryx Biopharmaceuticals (KERX) Stock Quote and News: